Recent publications on digital health technologies highlight the importance of ‘responsible’ use. References to the concept of responsibility are, however, frequently made without providing clear definitions of responsibility, thus leaving room for ambiguities. Addressing these uncertainties is critical since they might lead to misunderstandings, impacting the quality and safety of healthcare delivery. Therefore, this study investigates how responsibility is interpreted in the context of using digital health technologies, including artificial intelligence (AI), telemonitoring, wearables and mobile apps. We conducted a scoping (...) review with a systematic search in PubMed, Web of Science, Embase, CINAHL and Philosopher’s Index. A total of 34 articles were included and categorized using a theoretical framework of responsibility aspects, and revealed two main findings. First, we found that digital health technologies can expand and shift existing ‘role responsibilities’ among caregivers, patients and technology. Second, moral responsibility is often equated with liability or accountability, without clear justification. Articles describe new ways in which physicians can be held accountable, particularly in the context of AI, and discuss the emergence of a ‘responsibility gap’ where no-one can be fully responsible for AI-generated outcomes. The literature also shows that m-Health technologies can increase patients’ accountability for their own health. However, there was limited discussion in the reviewed literature on whether these attributions of accountability are appropriate. We conclude with implications for practice and suggestions for expanding the theoretical framework of moral responsibility, recommending further study on responsibility of collectives and artificial entities, and on the role of virtue in digital health. (shrink)

Rising rates of female incarceration within the United States are incompatible with the lack of federal standards outlining the rights of incarcerated mothers and their children. A robust body of evidence demonstrates that prison nurseries, programmes designed for mothers to keep their infants under their care during detainment or incarceration, provide essential and beneficial care that could not otherwise be achieved within the current carceral infrastructure. These benefits include facilitation of breastfeeding, bonding during a critical period of child development, and (...) decreased recidivism rates for participants. Legal precedent exists to support the rights of the mother to continue to parent their child but remains in stark opposition to current prison infrastructure that could allow them to do so. Existing state policies also have inconsistent mechanisms for determining child eligibility and should move to centre decision-making on a case-by-case basis. This work will demonstrate that a just society, supported by law and ensuring maternal–child welfare supports the establishment of prison nursery programmes as a part of the existing right to healthcare for incarcerated individuals. (shrink)

Using delay differential equations to study mathematical models of Parkinson's disease and Huntington's disease is important to show how important it is for synchronization between basal ganglia loops to work together. We used the delay circuit RLC (resistor, inductor, capacitor) model to show how the direct pathway and the indirect pathway in the basal ganglia excite and inhibit the motor cortex, respectively. A term has been added to the mathematical model without time delay in the case of the hyperdirect pathway. (...) It is proposed to add a non-linear term to adjust the synchronization. We studied Hopf bifurcation conditions for the proposed models. The desynchronization of response times between the direct pathway and the indirect pathway leads to different symptoms of Parkinson's disease. Tremor appears when the response time in the indirect pathway increases at rest. The simulation confirmed that tremor occurs and the motor cortex is in an inhibited state. The direct pathway can increase the time delay in the dopaminergic pathway, which significantly increases the activity of the motor cortex. The hyperdirect pathway regulates the activity of the motor cortex. The simulation showed bradykinesia occurs when we switch from one movement to another that is less exciting for the motor cortex. A decrease of GABA in the striatum or delayed excitation of the substantia nigra from the subthalamus may be a major cause of Parkinson's disease. An increase in the response time delay in one of the pathways results in the chaotic movement characteristic of Huntington's disease. (shrink)

Adrian Viens, Guest Editor of this Olivieri symposium, and Julian Savulescu, the Editor of JME, set the scene for the symposium."In failing...[her] when she needed them most, it is now clear that some members of the University’s Faculty of Medicine heard her muffled cries of academic freedom from the back room, yet their response was to serve another round of drinks and turn the music up louder. With the bombshell revelations in the...affair, the plug may have been pulled on this (...) business sponsored party, and hopefully a sober re-examination of the university’s neglected role and responsibility toward independent inquiry and academic freedom can begin.1" "These guys don’t get one thing—we’re not going away. This isn’t a personal vendetta. This is something I want patients to be protected from when I’m dead, fifty years from now.2" "[The Olivieri affair is] not a mystery novel, but instead the latest skulduggery at Toronto’s Hospital for Sick Children.1" "The legal assaults which you have endured in your battle against the drug company, and in your battle against the medical establishment appear to have been fought with the type of uncommon bravery that is rarely seen. It is for this reason that our trustees have unanimously chosen to recognise you for this most prestigious award.3" "[The Olivieri affair resulted from] a fundamental misreading of the issue as a mere contractual and scientific dispute...[it is] Canada’s worst academic and research scandal in decades...[Since 1998, Olivieri has been] demoted, then restored, then harassed. She has been smeared with allegations attacking her competence, integrity, sanity and personality....4"The Olivieri affair is one of the most important events to occur in research ethics. From its dominance in the Canadian and international news media, to changes in the governance of public health, academic medicine, …. (shrink)

Мета. Реконструювати точку зору Гоголя щодо його антропологічного проєкту, тобто виявити його відповіді на питання про те, що собою являє людина у вимірах сущого та належного. Інакше кажучи, йдеться про з’ясування позиції Гоголя щодо принципів існування українця в російській імперії. Теоретичний базис. Наш погляд на спадщину Гоголя базується на концептуальних положеннях феноменології, екзистенціалізму та герменевтики. Наукова новизна. Вперше зроблена спроба вивчити спадщину Гоголя як розробку антропологічного проєкту. В процесі її реалізації автори, звертаючись до біографії мислителя, його листування та текстів, реконструювали (...) основні виміри цього проєкту. Уважне ставлення до особливостей антропології Гоголя дозволяє наблизитися до розуміння теоретичних парадоксів світогляду письменника та чинників його ранньої смерті як особистої життєвої трагедії патріота України. Йдеться про те, що Гоголь в процесі пошуку форм реалізації свого високого покликання поставив перед собою задачу — обґрунтувати утопічну мету. Для нього шляхи розбудови росії як великої держави передбачають вихолощення базових цінностей європейської культури та приниження гідності людини. Висновки. В ході дослідження творів Миколи Гоголя автори виявили: а) важливість світоглядно-філософських питань; б) проблеми людини в його спадщині. Аргументовано, що Микола Гоголь, вирішуючи задачу окреслення загальних рис природи людини, на ранньому етапі творчості демонстрував оптимізм та виразні життєстверджуючі риси, укорінені в україноцентризмі. Істотні зміни в світогляді нашого мислителя зумовили його намагання обґрунтувати альтернативний європейському варіант антропологічного проєкту, що передбачає виправдання нікчемності пересічного жителя росії та й самої імперії ціною заперечення здобутків європейської філософії та науки. Болісне переживання цього теоретичного дисонансу стало передумовою ранньої трагічної смерті Миколи Васильовича. Нині вона є своєрідним попередженням про неможливість поєднати українську культуру та культуру росії, тобто небезпеку нігілістичного ставлення до здобутків європейської культури, невід’ємною складовою якої є Україна. Перспективи подальшого дослідження спадщини Гоголя автори повʼязують із зосередженням уваги на його: а) критиці Просвітництва та б) зʼясуванні форм змістовної укоріненості його творчості в українській філософії, насамперед у вченні Григорія Сковороди. (shrink)

The purpose of this study, which is part of a wider study of professional ethics, was to describe nurses’ perceptions of their rights in Italy. The data were collected by open-ended focus group interviews and analyzed with inductive content analysis. Based on the analysis, three main themes were identified. The first theme “Unfamiliarity with rights” described nurses’ perception that their rights mirrored historical roots, educational content, and nurses’ and patients’ position in the society. The second theme, “Rights reflected in legislation” (...) highlighted that working and professional Italian legislation played a strong role. The third theme, “Managerial barriers for nurses’ rights” underlined the nurses’ perceptions that nursing management had the responsibility to create the conditions where nurses’ rights could flourish. This study intends to contribute to the debate on this underexplored topic. (shrink)

During the period of extensive construction of communism in our country, when "the role of moral principles in the life of society is constantly increasing, and the sphere of action of the moral factor is expanding" , and when problems of moral education come to the fore, investigation of basic problems in the theory of morality becomes particularly pressing. One of these is the problem of a criterion for moral progress.

This article aims to explore representation of the content knowledge of historical Malay manuscripts by extracting the event features using an event ontology framework. The manuscript used during the testing is Sulalatus Salatin (Sejarah Melayu ) by Abdul Ahmad Samad and it was published at University of Malaya Digital Library database. In aligning to a domain-specific ontology, the Simple Event Model (SEM) model is adopted and an event-based ontology for historical Malay manuscripts is designed. Information extraction approach is done manually (...) to extract events from the manuscript and mapped into Protégé editor. Competency questions were constructed and submitted to the Protégé editor using SPARQL to check the ontology capability of providing answers as well as to examine its correctness. Event-based ontology model assists in discovering and representing the content knowledge of historical Malay manuscripts and supports organisation of knowledge. All the main concepts are extracted from selected Malay manuscript and 17 concepts used to develop the event-based ontology model. The knowledge was verified by three domain experts in Malay manuscript. In the findings, the interrater reliability for Event and Actor instances is 84%, which means 16% of instances and its type are incorrect and need amendment. For Place, interrater reliability is 95% and 99% for Role. Meanwhile, the experts achieved 100% agreement for Time. In addition, the experts agreed that the concepts, properties and instances for Malay Manuscript Ontology and complied with the criteria of consistency, completeness, conciseness, expandability and ease of use. The development of the event-based model of an ontology-based system with a high level of semantic granularity reflects the various cultural riches and intellectual aspect stored in Malay manuscripts. This will enable systematic research of the knowledge embedded in the manuscripts and make it widely and easily accessible by everyone. (shrink)

A simplified definition of point local clocks and the relationship between an inertial reference frame and a class of such clocks, at rest with respect to each other, are used for an algebraic determination of the geometry of Minkowski's space-time on the set of point events. The group of all automorphisms that preserve the time ordering induced by the set of all equivalent local clocks is shown to be generated by the inhomogeneous orthochronous Lorentz group and dilatations, consistently with a (...) well-known result of E. C. Zeeman. The existence of a universal limit velocity and of an invariant clock cone through any event is among the implications of our proof, thus effectively exploiting a suggestion due to F. Severi. (shrink)

Critical study of perception in perspectives of Indian philosophy and artificial intelligence.